Resources for Impact of Melatonin on COVID-19 [Updated for 2021]

The coronavirus (COVID-19) has been a drastic agent of change across the globe.
We’re learning new things about the virus every day, and scientists are hustling to create a viable vaccine.
Until then, scientific studies have made many other interesting discoveries. As blue-light scientists, we find melatonin’s success in treating viral symptoms especially fascinating.
Below, we’ve accumulated multiple scientific resources, news articles, and blog posts, covering the studies of melatonin and its impact on coronavirus symptoms.

Scientific Resources for the Impact of Melatonin on COVID-19


Us National Library of Medicine National Institutes of Health

“This article summarizes the likely benefits of melatonin in the attenuation of COVID-19 based on its putative pathogenesis.”

“On March 11th, 2020 during a media briefing, the World Health Organizati\aon (WHO) declared COVID-19 a pandemic as confirmed COVID-19 cases outside of China increased 13-fold and the number of countries affected tripled.”

“Melatonin is useful because of its ability to modulate the immune system, especially the critical function of suppressing cytokine storms to prevent progression of acute respiratory distress syndrome (ARDS) in infected patients.”

“Using network proximity analyses of drug targets and HCoV–host interactions in the human interactome, we prioritize 16 potential anti-HCoV repurposable drugs (e.g., melatonin, mercaptopurine, and sirolimus) that are further validated by enrichment analyses of drug-gene signatures and HCoV-induced transcriptomics data in human cell lines.”

“At a time of unprecedented panic over the rapidly spreading COVID-19 coronavirus, several research groups are asking whether existing therapies could be repurposed in fighting the disease. And pretty much everything seems to be on the table, including melatonin, the hormone that’s sold over-the-counter as a sleep aid.”

“The beneficial effects of melatonin can be explained by its properties as a potent antioxidant and antioxidant enzyme inducer, a regulator of apoptosis and a stimulator of immune functions.”

“So, if we could reduce the risk for vulnerable populations, it would make the COVID-19 pandemic more similar to other typical outbreaks. Children do not suffer from COVID-19 as much as their grandparents and have a much higher melatonin level.”

“The high mortality of deadly virus infectious diseases including SARS, MERS, COVID-19, and avian flu is often caused by the uncontrolled innate immune response and destructive inflammation.”

“However, several studies suggest that existing drugs or supplements, such as melatonin, may provide promising results for infections such as COVID-19, leading some professionals to wonder if doctors will soon be prescribing melatonin for coronavirus and other serious viruses in the future.”

“A recent review suggests that melatonin may play a role in combating COVID-19 as an adjuvant therapy; excessive inflammation, oxidation, and exaggerated immune responses during infection contributes to the cytokine storm that progresses into acute lung injury and acute respiratory distress syndrome and the antioxidant, anti-inflammatory, and immunomodulating effects of melatonin have been shown to be protective against viral induced ALI and ARDS.”

“Global “Melatonin SupplementsMarket “ Report 2020report recorddetailed estimation to improvement a complete information of the global Melatonin Supplements market today and its industrial outlook based completely on current and purpose marketplace.”

“Melatonin is an inexpensive and safe product with protective effect in both bacterial and viral infections likely due to its anti-inflammatory and anti-oxidative effects.”

EVMS Medical Group

“While there is very limited data (and none specific for COVID-19), the following “cocktail” may have a role in the prevention/mitigation of COVID-19 disease. While there is no high level evidence that this cocktail is effective; it is cheap, safe and widely available.”

News Articles for the impact of Melatonin on COVID-19

“”Melatonin could be a great, useful compound to counter the virus,” Neel said.”

“Pre-illness enhancement of innate immunity: The safest substances are vitamin D, low dose melatonin, probiotics, prebiotics and mushrooms.”

“Melatonin may not only help you sleep, but it seems it help with inflammation, oxidation, and immunomodulation which could potentially be protective against viral infections. Is well known that melatonin has immune enhancing properties, as well as being a strong antioxidant and antiviral.”

“Anti-arthritis drug Tocilizumab has already seemingly cured a raft of Covid-19 patients in China and Italy, and it has been promoted by a doctor alongside high-dose melatonin.”

“Medina County Texas Doctor Richard Neel announced this week that he is using high doses of Melatonin and Vitamin C to treat two patients for COVID-19 (both confirmed COVID cases), and it’s working.”

“”Sleep is such an important part of our health, especially the link between sleep and our immune system,” said Jose De Olazabal, a Pulmonologist at the Palm Beach Gardens Medical Center.”

“Most commonly used as a natural sleep aid, but due to its antioxidant, anti-inflammatory, immune enhancing characteristics could melatonin actually be  *a safer covid crushing underdog?”

“The Melatonin Market report focuses on the COVID-19 Outbreak Impact analysis of key points influencing the growth of the market.”

“The Melatonin market report that is recently published by Market Expertz is inclusive of all key players, current market scenario, regions that the market functions, strategies employed by the influential participants and applications of the products of this market.”

“The report on the global Melatonin market reveals that the market is expected to grow at a CAGR of ~XX% during the considered forecast period (2019-2029) and estimated to reach a value of ~US$XX by the end of 2029.”

“MarketResearch.Biz offers a 360-degree view of the global Melatonin, 5-HTP and Serotonin market and offers accurate forecasting and also covers competitive landscapes, with in-depth market segmentation including type segment, industry segment, channel segment etc., vital trends and strategic recommendations to enable our clients.”

“Risk for the coronavirus was reduced in those who had a pneumococcal polysaccharide or influenza vaccine, or were on melatonin, paroxetine, or carvedilol, according to Clinic research.”

Blog Articles for the Impact of Melatonin on COVID-19

“Melatonin is best known for its role in circadian rhythms and is used as a popular sleep aid. But research is finding that melatonin may have far more widespread applications.”

“Blue light, which is emitted by screens on your cell phone, computer, and tablet, and television, is known to hinder the production of melatonin.”

“In the hospitalized COVID-19 patients I have helped comanage, I find four drugs that may be considered as game-changers. These are hydroxychloroquine with azithromycin, tolicizumab and high-dose melatonin.”

“The worldwide Melatonin Market research report with impact of COVID-19 is considered to be an extremely intelligent and deep assessment on the present industrial conditions along with the overall Melatonin market size estimated from 2020 to 2026.”

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